Lecture: Bioinformatics II
Course
- Lecturer(s):
- Start: 25.10.2016
- Dates: Tue. 9:30-11:00 B-IT Marschallsaal
- Curriculum: B-IT Master Life Science Informatics
- Effort: 2 SWS / 3 CP
Exercises
- Tutor(s):
Description
This lecture starts on Tuesday, October 25.
Please subscribe to our mailing list for important information on the lecture and exercises!
In recent years, methods from visual computing have gained significant and increasing importance within bioinformatics. This is due to two main factors:
- Given ever-increasing volumes of sequencing data, suitable analysis and understanding of multi-dimensional data replaces data generation as the bottleneck in gaining biological insight. Graphical representations can augment our ability to reason about such data, and integrating them with automated data analysis allows scientists to better understand and steer data processing.
- Biology makes increasing use of digital images, primarily from microscopy and Magnetic Resonance Imaging (MRI). Performing quantitative analysis of such data requires suitable methods for image processing, including image registration and segmentation.
The range of available tools is as diverse as the research questions and methods in biology. Our class focuses on important basic principles of human perception, techniques for visualization of multi-dimensional data and graphs, image segmentation, registration, and statistical analysis, and provides some specific example applications within biology.
In addition to the lecture, students will complete two hands-on practical projects, one on data visualization, the other one on image processing, over the course of the semester.
Documents
- Exam-Grades (PDF document, 41 KB)
Slides
- Introduction (PDF document, 1.8 MB)
- Perception (PDF document, 1.7 MB)
- Multidimensional-Data (PDF document, 1.9 MB)
- Dimensionality-Reduction (PDF document, 1.4 MB)
- Graphs-Networks (PDF document, 1.8 MB)
- Visualization-Design (PDF document, 1.6 MB)
- Biological-Imaging (PDF document, 1.5 MB)
- Image-Segmentation (PDF document, 1.6 MB)
- Statistical-Image-Analysis (PDF document, 2.5 MB)
- Diffusion-MRI (PDF document, 1.9 MB)
Assignment Sheets
|
Exercise 1: Installation Assignment sheet (PDF document, 118 KB) |
|
Exercise 2: Data-manipulation Assignment sheet (PDF document, 147 KB)
|
|
Exercise 3: Scatter-Plot-Matrix Assignment sheet (PDF document, 108 KB) |
|
Exercise 4: Dimensionality-Reduction Assignment sheet (PDF document, 110 KB)
|
|
Exercise 5: Graph-Visualization Assignment sheet (PDF document, 128 KB) |
|
Exercise 6: Image-Processing Assignment sheet (PDF document, 117 KB)
|
|
Exercise 7: Gaussian-Mixture-Models Assignment sheet (PDF document, 174 KB) |
|
Exercise 8: MRFs Assignment sheet (PDF document, 110 KB)
|
|
Exercise 9: StatisticalImgAnalysis-GLM Assignment sheet (PDF document, 190 KB)
|